Alterations in basal nutrient metabolism increase resting energy expenditure in sickle cell disease

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Alterations in basal nutrient metabolism increase resting energy expenditure in sickle cell disease.

Basal rates of whole body protein, glucose, and lipid metabolism and resting energy expenditure (REE) were measured in eight African-American sickle cell disease (SCD) patients and in six African-American controls. Catheters were placed 1) in an antecubital vein for stable isotope infusion and 2) in a heated hand vein for arterialized venous blood. Breath and blood were collected during the las...

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Total and resting energy expenditure in children with sickle cell disease.

OBJECTIVE To investigate energy balance in children with sickle cell disease (SCD) as the possible cause of impaired growth and undernutrition. STUDY DESIGN Growth, resting (REE), total (TEE), and activity-related (AEE) energy expenditure and dietary intake were examined in 36 African American children with SCD (20 girls and 16 boys) and 30 control subjects (15 girls and 15 boys) of similar a...

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Intracardiac Thrombosis in Sickle Cell Disease

In patients with sickle cell disease, thrombotic microangiopathy is a rare complication. Also in sickle cell disease, intracardiac thrombus formation without structural heart diseases or atrial arrhythmias is a rare phenomenon. We herein describe a 22-year-old woman, who was a known case of sickle cell-βthalassemia, had a history of recent missed abortion, and was admitted with a vaso-occlusive...

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Equation to estimate resting energy expenditure in adolescents with sickle cell anemia1–3

Background: Basal energy requirements are higher in adolescents with sickle cell anemia (SCA) than in healthy control subjects. However, no equation is available to accurately predict their energy needs. Objective: Our objective was to develop a clinically useful equation to estimate resting energy expenditure (REE) in adolescents with SCA. Design: REE and other components of total energy expen...

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Equation to estimate resting energy expenditure in adolescents with sickle cell anemia.

BACKGROUND Basal energy requirements are higher in adolescents with sickle cell anemia (SCA) than in healthy control subjects. However, no equation is available to accurately predict their energy needs. OBJECTIVE Our objective was to develop a clinically useful equation to estimate resting energy expenditure (REE) in adolescents with SCA. DESIGN REE and other components of total energy expe...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism

سال: 1998

ISSN: 0193-1849,1522-1555

DOI: 10.1152/ajpendo.1998.274.2.e357